Description

Actins are highly conserved proteins expressed in all eukaryotic cells. This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with
other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).