| Pack Size | Cat No |
|---|---|
| 0.2 mL Concentrate | MM092-AA |
| 1.0 mL Concentrate | MM092-CC |
| 3.0 mL Predilute | MM092-3D |
| 6.0 mL Predilute | MM092-6D |
Cytokeratin 18 together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in
single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
| Alternative Name | CYK 18, PIG46, KRT18 |
| Species | Mouse |
| Clone | DC10 |
| Isotype | IgG1 Kappa |
| Dilution Range | Assay dependent |
| Species Reactivity | Human |
| Application | IHC |
| Cell Localization | Cytoplasm |
| Positive Control | Human breast carcinoma, Skin, Small intestine, Hepatocellular carcinoma and Prostate adenocarcinoma. |
1. Ines Aurich et al, Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers. Gut. 2007 March.
2.N. Dobashi et a, l Elevation of Anti-Cytokeratin 18 Antibody and Circulating Cytokeratin 18. AntiCytokeratin 18 Antibody Immune Complexes in Sera of Patients with Idiopathic Pulmonary Fibrosis. Lung, 2000.
