| Pack Size | Cat No |
|---|---|
| 0.2 mL Concentrate | MM018-AA |
| 1.0 mL Concentrate | MM018-CC |
| 3.0 mL Predilute | MM018-3D |
| 6.0 mL Predilute | MM018-6D |
The Estrogen receptor is a ~ 67kDa protein. The estrogen receptor gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. Many investigators have reported on the isolation of cDNAs which encode variant ER sequences. Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligandactivated transcription factors.
| Alternative Name | ESR1, ESR, NR3A1 |
| Species | Mouse |
| Clone | C-70 |
| Isotype | Mouse IgG1 Kappa |
| Dilution Range | Assay dependent |
| Species Reactivity | Human |
| Application | IHC |
| Cell Localization | Nuclear |
| Positive Control | Breast carcinoma |
1. Cagatay Arslan, MD et al, Estrogen receptor immunohistochemistry cutoff value: Standardization is needed,Human Pathology, Jan 2010.
2. Sheila Cristina Lordelo Wludarski et al, Estrogen and progesterone receptor testing in breast carcinoma: concordance of results between local and reference laboratories in Brazil, Sao Paulo Med. J, 2011.
