Description
BioMarq GMS Stain Kit is used for in vitro diagnostic use. GMS Stain is intended for use in the histologic visualization of fungi, basement membrane and some opportunistic organisms such as Pneumocystis carinii. Pneumocystis carinii is an opportunistic pathogen that causes severe pulmonary disease in humans with acquired, induced, or inherited immune deficiency syndromes. Also the stain helps in identification of Actinomyces, Nocardia and related species.
The polysaccharide molecules in the cell wall of fungi are oxidized with chromic acid to di aldehydes which are then precipitated with silver solution there by staining fungi grey /black. Gold chloride acts as an intensifier & Hypo removes unreduced silver. The counter stain here is light green.