| Pack Size | Cat No |
|---|---|
| 0.2 mL Concentrate | RM019-AA |
| 1.0 mL Concentrate | RM019-CC |
| 3.0 mL Predilute | RM019-3D |
| 6.0 mL Predilute | RM019-6D |
The Ki-67 is a nuclear protein. It is established as a reference marker for assessing cellular proliferation in tumor cells. This antibody identifies actively dividing cells at all stages of cell cycle except G0 phase. In histopathological diagnosis Ki-67 is used as a marker for identifying certain malignances of blood and solid tumor in proliferating tumors. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms.
| Alternative Name | MKI67, marker of proliferation Ki-67, KIA, MIB-, MIB-1, PPP1R105 |
| Species | Rabbit |
| Clone | EPR3610 |
| Isotype | Rabbit IgG |
| Dilution Range | Assay dependent |
| Species Reactivity | Human |
| Application | IHC |
| Cell Localization | Nuclear |
| Positive Control | Tonsil or Breast carcinoma |
1. Pena LL et al, Immunohistochemical detection of Ki-67 and PCNA in canine mammary tumors: relationship to clinical and pathologic variables, J Vet Diagn Invest. 1998 Jul 10, 237-46.
2. Shruthi PJ et al, Nucleolar Organizer Region Count, PCNA and Ki-67 Indices are Diagnostic Markers of Malignancy and Cell Proliferation Rate in Bovine Lymphosarcoma, Journal of Veterinary Science & Technology, 2016, Feb 12.
