| Pack Size | Cat No |
|---|---|
| 0.2 mL Concentrate | MM031-AA |
| 1.0 mL Concentrate | MM031-CC |
| 3.0 mL Predilute | MM031-3D |
| 6.0 mL Predilute | MM031-6D |
The Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) The PR gene produces intracellular receptors which bind to DNA & regulates gene expression of estrogen receptor The Progesterone protein is identified in nucleus of both steroid occupied & steroid unoccupied cells in tissues. PR is expressed in breast carcinoma, endometrial carcinoma, ovarian carcinoma & meningioma’s.
| Alternative Name | PGR, NR3C3 |
| Species | Mouse |
| Clone | PR484 |
| Isotype | Mouse IgG1 Kappa |
| Dilution Range | Assay dependent |
| Species Reactivity | Human |
| Application | IHC |
| Cell Localization | Nuclear |
| Positive Control | Breast carcinoma |
1. Syed K Moshin et al, Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study, Modern Pathology (2004) 17, 1545–1554 (2004).
2. Megan L. Troxell et al Comparison of Estrogen and Progesterone Receptor Antibody Reagents Using Proficiency Testing Data, Archives of Pathology & Laboratory Medicine: October 2017, Vol. 141, No. 10, pp. 1402-1412 .
