CD57

CD57

Pack Size Cat No
0.2 mL Concentrate MM009-AA
1.0 mL Concentrate MM009-CC
3.0 mL Predilute MM009-3D
6.0 mL Predilute MM009-6D
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Description

The specific antibody recognizes a 110 kDa protein on Natural killer (NK) cell surface that is identified as CD57. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Cd57 antibody is involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. It can also play a role in glycosaminoglycan biosynthesis. In HCMV (Human cytomegalovirus) there observed an increased number of
CD57 positive natural killer cells.CD57 expression has been regarded as a marker of terminal differentiation of anergy & senescence.

Specifications

Alternative Name B3GAT1, GLCATP
Species Mouse
Clone NK/804
Isotype Mouse IgM
Dilution Range Assay dependent
Species Reactivity Human
Application IHC
Cell Localization Golgi apparatus
membrane.
Positive Control Tonsil & Brain

DataSheet & SDS

Download Data Sheet
Download SDS Sheet

References

1. Carolyn M. Nielsen et al, Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease, Front Immunol, 2013.

2. Kared H1 et al, CD57 in human natural killer cells and Tlymphocytes, Cancer Immunol Immunother, 2016.

3. Pileri SA et al, Antigen retrieval techniques in
immunohistochemistry, Comparison of different methods. J Pathol. 1997 Sep.

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